Palmitoyl pentapeptide-4 hangata e sebelisoa e le gel ea motheo bakeng sa lihlahisoa tsa tlhokomelo ea letlalo tse thibelang wrinkles.
Palmitoyl pentapeptide-4 (pele ho 2006 palmitoyl pentapeptide-3) hangata e sebelisoa e le gel ea motheo bakeng sa lihlahisoa tsa tlhokomelo ea letlalo tse thibelang wrinkles.Ke moetsi oa motsoako oa motsoako oa letlalo oa Spain ka 2000 e le indasteri ea bona ea tlhokomelo e le motsoako o sebetsang, palmitoyl pentapeptide-4 ke letoto la peptide ea ts'ebeliso ea pele le polypeptide e sebelisoang ka ho fetesisa, lihlahisoa tse tsebahalang tsa malapeng le kantle ho naha li sebelisoa haholo joalo ka. motsoako o ka sehloohong o sebetsang oa tlhokomelo ea letlalo le thibelang wrinkles, lihlahisoa tse ngata tsa tlhokomelo ea letlalo tse khahlanong le wrinkle hangata li hlaha setšoantšong sa eona.Ka ho eketsa collagen ka dermis, e ka fetola mokhoa oa botsofali ka ho tsosolosa letlalo ho tloha ka hare.E ama collagen, li-elastic fibers le hyaluronic acid lia eketseha, li eketsa mongobo oa letlalo le ho boloka mongobo, li eketsa botenya ba letlalo le ho fokotsa mela e metle.
Palmitoyl pentapeptide-4 (Pal-lys-thr-Lys-ser = Pal-KTTKS) e na le li-amino acid tse hlano tse hokahantsoeng le liketane tsa 16-carbon aliphatic ho ntlafatsa ho kenella ha molek'hule ka sebopeho sa lipid sa letlalo.Ena ke margarine.Palmitoyl pentapeptide-4 ke peptide ea lenģosa e laolang ho sebetsa ha sele ka ho sebelisana le li-receptor tsa bona tse khethehileng.Ba ile ba kenya tšebetsong liphatsa tsa lefutso tse amehang ntlafatsong ea matrix a extracellular le ho ata ha lisele.Palmitoyl pentapeptide-4 e na le phello e khahlanong le wrinkles le ho tiisa letlalo ka ho kenya tšebetsong motsoako o mocha oa li-macromolecules ka har'a matrix a extracellular.
Mokhoa oa ts'ebetso
Lithuto tsa in vitro li fumane keketseho ea 212% ea mofuta oa I collagen synthesis, keketseho ea 100% ho 327% ea mofuta oa IV collagen synthesis, le keketseho ea 267% ea motsoako oa hyaluronic acid.Collagen I e fumanoa mefuteng e mengata ea 19 ea collagen 'meleng.Ka hona, ho eketsa tlhahiso ea kakaretso ea collagen I ho na le phello e kholo ho tsosolosa letlalo.Liphuputso tsa likhoeli tse tšeletseng tsa li-vivo li fumane phokotso ea karolelano ea karolo ea 17 lekholong botebong ba mela e metle, karolo ea 68 lekholong sebakeng sa mela e tebileng e tebileng, karolo ea 51 lekholong sebakeng sa mela e metle e itekanetseng, le karolo ea 16 lekholong ea likhoele tse thata. letlalo.
Nako ea poso: Apr-28-2023